Transdermal Magnesium patches.
Magnesium helps to regulate cholesterol levels and tends to get depleted when we are under pressure. Too little magnesium may trigger headaches and fatigue leading to stress. One cup of spinach goes a long way in replenishing magnesium stores. Magnesium helps to keep our nerves and muscles relaxed and prevent them from becoming overexcited; a deficiency of which can lead to muscle tension, cramps and fatigue. Spinach is a magnesium powerhouse, and also a good source of vitamin A, C, iron and foliates. One cup of fresh spinach or half a cup of cooked spinach a day is a stress relaxant. Low potassium levels can cause muscle tiredness, fatigue, irritability and anxiety. Broccoli is a source of natural potassium; it is also rich in beta-carotene, vitamins C and E that strengthen immune system. With A (HINI) on the loose, it is wise to eat a few servings of broccoli each week.
Also magnesium as pain-reducing effects.
"Curcumin pre-treatment decreased the zinc and magnesium levels and increased iron level when
compared to the Cd-only treated group. Curcumin treatment alone decreased the level of calcium and magnesium in comparison to the control group of mice"
Another well-recognized natural product-derived molecule is curcumin, which has more than 100 different targets, among them TRPV1 [69,70]. Curcumin reduces capsaicin-induced calcium rise and inward current in DRG neurons of both mice and rats [69] by antagonizing TRPV1 receptors [71].
Edit:
combination of magnesium, curcumin and capsaicin?